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Title	Application of digital signal analysis, mass data acquisition and processing techniques, and automated experiment protocols to the study of cardiac cell membrane electrophysiology, with mathematical modeling
Author	Buckles, David S.
Date	1987
Affiliation/College	College of Graduate Studies
Department	Biometry
Extent	iii, 123 leaves : ill.; 29 cm
Source	QT 34 B924a 1987
Subject.MeSH	Signal Processing, Computer-Assisted Models, Theoretical Data Collection--methods Electrophysiology--methods Academic Dissertations
Collection	MUSC Theses and Dissertations
Contributing Institution	Waring Historical Library (MUSC)
Rights	Copyright is held by the author.
Language	English
Type	Text
Format	application/pdf
Media Type	Manuscripts
Resource Identifier	mtd1987_buckles_ds
Abstract	Traditional methods of collecting, analyzing and storing data from cardiac cell membrane electrophysiology experiments have become increasingly cumbersome and unwieldy as experimental protocols have become more sophisticated and complex. A global approach to collecting, analyzing, refining and storing electrophysiologic data, as well as a new approach to mathematical modeling of cell membrane single ion channel kinetics, was developed. This utilizes a comprehensive microcomputer based system of software with specialized analog and digital electronics for data acquisition, analysis and archiving. Unique discrete signal processing techniques for characterizing the electronic recording system, including specialized hardware and software adapted for minimizing distortions in biosignal recordings, are discussed in detail.

Application of digital signal analysis, mass data acquisition and processing techniques, and automated experiment protocols to the study of cardiac cell membrane electrophysiology, with mathematical modeling

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